Eukaryotic Translation Initiation Factor 4F

Preferred Label : Eukaryotic Translation Initiation Factor 4F;

NCIt synonyms : eIF4F; eIF-4F;

NCIt definition : A protein complex comprised of a heterotetrameric core, eukaryotic initiation factor 4A, 4E, and 4 gamma, bound to other factors; the exact composition of varies with the cellular environmental conditions. This complex recognizes the 5' cap of mRNA and promotes the initiation of translation.;

Details

Origin ID

C128282;

UMLS CUI

C0058989;

Automatic exact mappings (from CISMeF team)
- Eukaryotic translation initiation factor 4E [ORDO Gene]
- eukaryotic initiation Factor-4F [MeSH Descriptor]
- eukaryotic translation initiation factor 4 gamma 1 [ORDO Gene]
- eukaryotic translation initiation factor 4F complex [GO term]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- eukaryotic initiation Factor-4F [MeSH Descriptor]
- eukaryotic initiation Factor-4F [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_has_biochemical_function
- Initiation Factor [NCIt concept]
- RNA Helicase [NCIt concept]
gene_product_plays_role_in_biological_process
- Translation Process [NCIt concept]
has_gene_product_element
- Eukaryotic Initiation Factor 4A-I [NCIt concept]
- Eukaryotic Initiation Factor 4A-II [NCIt concept]
- Eukaryotic Translation Initiation Factor 4 Gamma 1 [NCIt concept]
- Eukaryotic Translation Initiation Factor 4 Gamma Family [NCIt concept]
- Eukaryotic Translation Initiation Factor 4A Family [NCIt concept]
- Eukaryotic Translation Initiation Factor 4E [NCIt concept]
- Eukaryotic Translation Initiation Factor 4E Type 2 [NCIt concept]

Keyword's position in hierarchy(ies) :

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