Eukaryotic Translation Initiation Factor 4A Family

Preferred Label : Eukaryotic Translation Initiation Factor 4A Family;

NCIt synonyms : eIF-4A Family; Eukaryotic Initiation Factor 4A; eIF4A; eIF4A Family; Eukaryotic Initiation Factor 4A Family; eIF-4A;

NCIt definition : A family of proteins that are part of the eukaryotic translation initiation factor 4F complex (eIF4F). The members of the eIF4A family act as an ATP-dependent RNA helicases and unwind 5' UTRs of mRNA to promote ribosomal binding and translation.;

NCI Metathesaurus CUI : CL1647681;

Details

Origin ID

C178136;

UMLS CUI

C5552898;

Automatic exact mappings (from CISMeF team)
- eukaryotic initiation Factor-4A [MeSH Descriptor]
Biochemical function of gene products
- Eukaryotic Initiation Factor 4A-I [NCIt concept]
- Eukaryotic Initiation Factor 4A-II [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_has_biochemical_function
- Initiation Factor [NCIt concept]
- RNA Helicase [NCIt concept]
gene_product_is_physical_part_of
- Eukaryotic Translation Initiation Factor 4F [NCIt concept]
gene_product_plays_role_in_biological_process
- Translation Initiation [NCIt concept]
is_target
- Zotatifin [NCIt concept]

Keyword's position in hierarchy(ies) :

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