Lymphocyte Activation Gene 3 Protein

Preferred Label : Lymphocyte Activation Gene 3 Protein;

NCIt synonyms : Protein FDC; CD223 Antigen; LAG-3; LAG3;

NCIt definition : Lymphocyte activation gene 3 protein (525 aa, 57 kDa) is encoded by the human LAG3 gene. This protein is involved in the activation of T-cells and natural killer cells.;

Details

Origin ID

C104623;

UMLS CUI

C1456336;

Automatic exact mappings (from CISMeF team)
- CD223 antigen [MeSH concept]
- Lymphocyte activation gene 3 [OMIM gene]
Currated CISMeF NLP mapping
- Lymphocyte Activation Gene 3 Protein [MeSH Descriptor]
- Lymphocyte Activation Gene 3 Protein [MeSH concept]
OMIM relation
- Lymphocyte activation gene 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Lag3 protein, human [MeSH concept]
- Lag3 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Immunoprotein Gene [NCIt concept]
- LAG3 Gene [NCIt concept]
gene_product_plays_role_in_biological_process
- Immune System Process [NCIt concept]
is_target
- Anti-LAG-3 Monoclonal Antibody HLX26 [NCIt concept]
- Anti-LAG-3 Monoclonal Antibody LBL-007 [NCIt concept]
- Anti-LAG-3 Monoclonal Antibody Sym022 [NCIt concept]
- Anti-LAG-3 Monoclonal Antibody TQB2223 [NCIt concept]
- Anti-LAG-3/Anti-PD-L1 Bispecific Antibody IBI323 [NCIt concept]
- Anti-LAG-3/PD-1 Bispecific Antibody INCA32459 [NCIt concept]
- Anti-LAG-3/PD-L1 Bispecific Antibody FS118 [NCIt concept]
- Anti-LAG-3/TIGIT Bispecific Antibody ZGGS15 [NCIt concept]
- Anti-PD-1/LAG-3 Bispecific Antibody AK129 [NCIt concept]
- Anti-PD-1/LAG-3 Bispecific Antibody EMB-02 [NCIt concept]
- Brivestobart [NCIt concept]
- Encelimab [NCIt concept]
- Favezelimab [NCIt concept]
- Favezelimab/Pembrolizumab Formulation [NCIt concept]
- Fianlimab [NCIt concept]
- Ieramilimab [NCIt concept]
- Miptenalimab [NCIt concept]
- Negalstobart [NCIt concept]
- Nivolumab/Relatlimab-rmbw [NCIt concept]
- Pavunalimab [NCIt concept]
- Relatlimab [NCIt concept]
- Tobemstomig [NCIt concept]
- Tuparstobart [NCIt concept]
- Zirconium Zr 89-DFO-fianlimab [NCIt concept]

Keyword's position in hierarchy(ies) :

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