Transcription Factor 7

Preferred Label : Transcription Factor 7;

NCIt synonyms : TCF-7; TCF-1; T-Cell Factor 1; TCF7; T-Cell-Specific Transcription Factor 1;

NCIt definition : Transcription factor 7 (384 aa, 42 kDa) is encoded by the human TCF7 gene. This protein is involved in both thymocyte survival and the regulation of transcription.;

NCIt note : Transcription factor 7 binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3'). (UniProt);

Details

Origin ID

C97908;

UMLS CUI

C0286910;

Automatic exact mappings (from CISMeF team)
- Hnf1 homeobox a [OMIM gene]
- Transcription factor 7 [OMIM gene]
- t cell transcription factor 1 [MeSH Descriptor]
- transcription factor 7 [HGNC gene]
OMIM relation
- Transcription factor 7 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- T cell transcription factor 1 [MeSH concept]
- TCF7 protein, human [MeSH concept]
- TCF7 protein, human [MeSH Supplementary Concept]
- t cell transcription factor 1 [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- TCF7 Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_expressed_in_tissue
- Intestinal Epithelium [NCIt concept]
- Mammary Epithelium [NCIt concept]
- T-Lymphocyte [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- HMG-Box [NCIt concept]
gene_product_is_element_in_pathway
- Acute Myeloid Leukemia Pathway [NCIt concept]
- Adherens Junction Assembly Pathway [NCIt concept]
- Arrhythmogenic Right Ventricular Cardiomyopathy Pathway [NCIt concept]
- Basal Cell Carcinoma Pathway [NCIt concept]
- Colorectal Cancer Pathway [NCIt concept]
- Endometrial Cancer Pathway [NCIt concept]
- Melanogenesis Pathway [NCIt concept]
- Papillary Thyroid Carcinoma Pathway [NCIt concept]
- Prostate Cancer Pathway [NCIt concept]
- Wnt Signaling Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Immune Response Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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