JAK1 wt Allele

Preferred Label : JAK1 wt Allele;

NCIt synonyms : JAK1A; Janus Kinase 1 wt Allele; Janus Kinase 1 (A Protein Tyrosine Kinase) Gene; JTK3; JAK1B;

NCIt definition : Human JAK1 wild-type allele is located within 1p32.3-p31.3 and is approximately 53 kb in length. This allele, which encodes tyrosine-protein kinase JAK1 protein, plays a role in signal transduction in the IFN (alpha, beta and gamma) signaling pathways.;

GenBank Accession Number : NM_002227;

Details

Origin ID

C51083;

UMLS CUI

C1708580;

OMIM relation
- Janus kinase 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 1: 65064007-65012229 [NCIt concept]
gene_in_chromosomal_location
- 1p32.3-p31.3 [NCIt concept]
gene_is_element_in_pathway
- EGF Signaling Pathway [NCIt concept]
- IFN Alpha Signaling Pathway [NCIt concept]
- IFN Gamma Signaling Pathway [NCIt concept]
- IL10 Anti-inflammatory Signaling Pathway [NCIt concept]
- IL2 Signaling Pathway [NCIt concept]
- IL22 Signaling Pathway [NCIt concept]
- IL2RB Pathway [NCIt concept]
- IL4 Signaling Pathway [NCIt concept]
- IL7 Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- Leishmaniasis Infection Pathway [NCIt concept]
- PDGF Signaling Pathway [NCIt concept]
- Pancreatic Cancer Pathway [NCIt concept]
- Stat3 Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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