" /> CCND1 wt Allele - CISMeF





Preferred Label : CCND1 wt Allele;

NCIt synonyms : PRAD1; U21B31; BCL1; D11S287E; Cyclin D1 wt Allele;

NCIt definition : Human CCND1 wild-type allele is located within 11q13 and is approximately 13 kb in length. This allele, which encodes G1/S-specific cyclin-D1 protein, plays a role in the regulation of the cell cycle during the G1/S transition. Aberrant allelic expression caused by mutations, amplification and overexpression alters cell cycle progression. These abnormal alterations have been frequently identified in a variety of tumors and may contribute to tumorigenesis.;

GenBank Accession Number : Z23022;

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12/05/2024


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