" /> CDK2 wt Allele - CISMeF





Preferred Label : CDK2 wt Allele;

NCIt synonyms : Cell Division Kinase 2 Gene; Cell Division Protein Kinase 2 Gene; p33(CDK2) Gene; CDC2-Related Protein Kinase Gene; p33 Protein Kinase Gene; Cyclin-Dependent Kinase 2 Isoform 2 Gene; Cyclin-Dependent Kinase 2 Isoform 1 Gene; Cyclin Dependent Kinase 2 wt Allele;

NCIt definition : Human CDK2 wild-type allele is located within 12q13 and is approximately 6 kb in length. This allele, which encodes cyclin-dependent kinase 2 protein, is involved in cell cycle regulation and DNA synthesis. This allele is essential for the transit of the cell through the G1/S phase transition.;

NCIt note : The CDK2 gene has two alternatively spliced variants and multiple transcription initiation. The N-terminal domain interacts with cyclins and the C-terminal domain interacts with CSK1.;

GenBank Accession Number : NM_052827;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
12/05/2024


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.