Ras-Specific Guanine Nucleotide-Releasing Factor 1

Preferred Label : Ras-Specific Guanine Nucleotide-Releasing Factor 1;

NCIt synonyms : CDC25; GRF55; Guanine Nucleotide-Releasing Factor, 55KD; RASGRF1; GNRP; GRF1; H-GRF55; Ras-Specific Nucleotide Exchange Factor CDC25; Ras-GRF1; Ras Protein Specific Guanine Nucleotide Releasing Factor 1; Guanine Nucleotide Exchange Factor; Guanine Nucleotide-Releasing Factor, 55 kD; Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1; Guanine Nucleotide-Releasing Factor, 55-kD; Guanine Nucleotide-Releasing Protein; Guanine Nucleotide-Releasing Factor 1;

NCIt definition : Ras-specific guanine nucleotide-releasing factor 1 (1273 aa, 145 kDa) is encoded by the human RASGRF1 gene. This protein plays a role in guanine nucleotide exchange for Ras proteins.;

Details

Origin ID

C42627;

UMLS CUI

C1675721;

OMIM relation
- Ras protein-specific guanine nucleotide-releasing factor 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- RASGRF1 protein, human [MeSH Supplementary Concept]
- RASGRF1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- RASGRF1 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- DH Domain [NCIt concept]
- PH Domain [NCIt concept]
gene_product_is_element_in_pathway
- CDC25 and CHK1 Regulatory Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- G2/M Checkpoint Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- RB Checkpoint Signaling Pathway [NCIt concept]
- SRC Tyrosine Kinase Activation Pathway [NCIt concept]
- Sonic Hedgehog Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Memory [NCIt concept]
- Post-Translational Modification [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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