NCIt definition : T-cell antigen CD7 (240 aa, 25 kDa) is encoded by the human CD7 gene. This protein
plays a role in the development and function of lymphoid cells.;
NCIt note : Expressed in thymocytes and mature T cells by human CD7 Gene (Immunoglobulin Superfamily),
240-aa 25-kDa (precursor) T-Cell Antigen CD7 is a cell surface type I transmembrane
glycoprotein that interacts with SECTM1, contains an Ig-like domain, and is essential
in T-cell interactions and in T-cell/B-cell interaction during early lymphoid development.
One of the earliest antigens on cells of the T-lymphocyte lineage, CD7 is the most
reliable clinical marker of T-cell acute lymphocytic leukemia.;