Preferred Label : Anti-CD7 CAR-T Cells RD13-02;
NCIt synonyms : Anti-CD7 CAR T-cells RD13-02; CD7 CAR-T Cells RD13-02; Anti-CD7 CAR T Cells RD13-02;
NCIt definition : A preparation of T-lymphocytes that have been genetically engineered to express a
chimeric antigen receptor (CAR) directed against the tumor-associated antigen (TAA)
CD7, with potential immunostimulating and antineoplastic activities. Upon administration,
anti-CD7 CAR-T cells RD13-02 specifically target and kill CD7-expressing tumor cells.
CD7 is a transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells
and their precursors. It is expressed in the majority of lymphoblastic T-cell leukemias
and lymphomas and in a subset of peripheral T-cell lymphomas.;
Molecule name : RD13-02; RD13 02;
NCI Metathesaurus CUI : CL1915062;
Origin ID : C200796;
UMLS CUI : C5854582;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
- has_target
