Preferred Label : Allogeneic Anti-CD7 CAR T Cells 4SCAR7U;
NCIt synonyms : Allogeneic Anti-CD7 CAR-T Cells 4SCAR7U; Allogeneic Anti-CD7 CAR T-cells 4SCAR7U; Allogeneic CD7-targeting Universal CAR T Cells 4SCAR7U; Universal CD7-specific CAR Gene-engineered T Cells 4SCAR7U; 4SCAR7U T Cells; Allogeneic Anti-CD7 4SCAR-expressing T-cells 4SCAR7U;
NCIt definition : A preparation of allogeneic, off-the-shelf (OTS), universal, gene-edited T-lymphocytes
expressing a fourth-generation chimeric antigen receptor (CAR) specific for the tumor-associated
antigen (TAA) CD7, with potential immunostimulating and antineoplastic activities.
Upon administration, allogeneic anti-CD7 CAR T cells 4SCAR7U specifically target and
kill CD7-expressing tumor cells. CD7 is a transmembrane glycoprotein expressed by
T-cells and natural killer (NK) cells and their precursors. It is expressed in the
majority of lymphoblastic T-cell leukemias and lymphomas and in a subset of peripheral
T-cell lymphomas.;
Molecule name : 4SCAR7U;
NCI Metathesaurus CUI : CL1920595;
Origin ID : C201295;
UMLS CUI : C5854649;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
- has_target
