Complement Component C8 Alpha Chain

Preferred Label : Complement Component C8 Alpha Chain;

NCIt synonyms : C8A; Complement C8 Alpha Chain; Complement Component C8A; C8 Alpha; Complement Component 8 Subunit Alpha; Complement Component 8 Alpha Subunit;

NCIt definition : Complement component C8 alpha chain (584 aa, 65 kDa) is encoded by the human C8A gene. This protein is involved in membrane localization of the terminal complement complex.;

NCI Metathesaurus CUI : CL1648066;

Details

Origin ID

C178608;

UMLS CUI

C5552851;

Automatic exact mappings (from CISMeF team)
- Complement component 8, alpha subunit [OMIM gene]
- complement C8 [MeSH Descriptor]
- complement C8 alpha chain [HGNC gene]
- complement C8 alpha chain [ORDO Gene]
OMIM relation
- Complement component 8, alpha subunit [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
gene_encodes_gene_product
- C8A Gene [NCIt concept]
- Complement Component Gene [NCIt concept]
gene_product_has_biochemical_function
- Complement [NCIt concept]
gene_product_has_structural_domain_or_motif
- EGF-Like Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Amoebiasis Pathway [NCIt concept]
- Complement and Coagulation Cascade [NCIt concept]
- Prion Disease Pathway [NCIt concept]
- Systemic Lupus Erythematosus Pathway [NCIt concept]
gene_product_is_physical_part_of
- Complement Component C8 [NCIt concept]
- Membrane Attack Complex [NCIt concept]
gene_product_plays_role_in_biological_process
- Activation of Membrane Attack Complex [NCIt concept]
- Complement Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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