complement C8 - CISMeF

Preferred Label : complement C8;

MeSH definition : A 150-kDa serum glycoprotein composed of three subunits with each encoded by a different gene (C8A; C8B; and C8G). This heterotrimer contains a disulfide-linked C8alpha-C8gamma heterodimer and a noncovalently associated C8beta chain. C8 is the next component to bind the C5-7 complex forming C5b-8 that binds COMPLEMENT C9 and acts as a catalyst in the polymerization of C9.;

MeSH synonym : c8, complement; c8 complement; component 8, complement; complement 8; complement component 8; complement, C8;

Wikipedia automatic translation : C8;

MeSH hyponym : complement component C8 gamma; complement component C8 alpha; complement component C8 beta; Complement Component C8 beta Chain; Complement Component C8 gamma Chain; Complement Component C8 alpha Chain;

Wikipedia link : https://en.wikipedia.org/wiki/C8;

Is substance : O;

Details

Origin ID

D003185;

UMLS CUI

C0009525;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Indexing information
- CD59 protein, human [MeSH Supplementary Concept]
Pharmacological action(s)
- immunologic factors [MeSH Descriptor]
Record concept(s)
- complement C8 [MeSH concept]
- complement component C8 alpha [MeSH concept]
- complement component C8 beta [MeSH concept]
- complement component C8 gamma [MeSH concept]
Related MeSH Supplementary Concept(s)
- C8G protein, human [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Complement C8 [LOINC component]
- Complement component C8 (substance) [SNOMED CT concept]
- complement component c8 [SNOMED Notion]
Validated automatic mappings to BTNT
- Complement component C8 (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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