V-Set Domain-Containing T-Cell Activation Inhibitor 1

Preferred Label : V-Set Domain-Containing T-Cell Activation Inhibitor 1;

NCIt synonyms : Protein B7S1; T-Cell Costimulatory Molecule B7x; B7h.5; Immune Costimulatory Protein B7-H4; VTCN1; B7 Homolog 4;

NCIt definition : V-set domain-containing T-cell activation inhibitor 1 (282 aa, 31 kDa) is encoded by the human VTCN1 gene. This protein plays a role in the inhibition of T-cell functions.;

Details

Origin ID

C106223;

UMLS CUI

C1259813;

Automatic exact mappings (from CISMeF team)
- V-Set Domain-Containing T-Cell activation inhibitor 1 [MeSH Descriptor]
- V-Set Domain-Containing T-Cell activation inhibitor 1 [MeSH concept]
- V-set domain-containing t-cell activation inhibitor 1 [OMIM gene]
OMIM relation
- V-set domain-containing t-cell activation inhibitor 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- VTCN1 protein, human [MeSH Supplementary Concept]
- VTCN1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Immunoprotein Gene [NCIt concept]
- VTCN1 Gene [NCIt concept]
gene_product_expressed_in_tissue
- Activated Lymphocyte [NCIt concept]
- Dendritic Cell [NCIt concept]
- Monocyte [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like V-Type Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Immune System Process [NCIt concept]
- Interferon Signaling Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
- Negative Regulation of Lymphocyte Activation [NCIt concept]
is_target
- Alsevalimab [NCIt concept]
- Anti-B7-H4 Antibody-drug Conjugate SGN-B7H4V [NCIt concept]
- Anti-B7-H4 Antibody-drug Conjugate XMT-1660 [NCIt concept]
- Anti-B7-H4 Monoclonal Antibody NC762 [NCIt concept]
- Anti-B7-H4/ TOP1i Antibody-drug Conjugate AZD8205 [NCIt concept]
- Anti-B7-H4/Anti-4-1BB Bispecific Antibody CLN-418 [NCIt concept]
- Anti-B7-H4/Anti-CD3 Bispecific Antibody GEN1047 [NCIt concept]
- Anti-B7-H4/Anti-CD3 Bispecific Antibody PF-07260437 [NCIt concept]

Keyword's position in hierarchy(ies) :

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