serum-glucocorticoid regulated kinase

Preferred Label : serum-glucocorticoid regulated kinase;

MeSH note : highly regulated at the transcriptional level by glucocorticoid hormones & serum; suggests a novel interplay between glucocorticoid receptor signalling & a protein kinase of the second messenger family; may play a role in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion; amino acid sequence given in first source; RefSeq NM_011361 (mouse), NM_005627 (human), NM_019232 (rat);

CISMeF synonym : EC 2.7.1.37 (SGK2 protein, human); SGK1 protein, human; SGK1 protein, rat; SGK1 protein, xenopus; SGK2 protein, human; Sgk1 protein, mouse; Sgk2 protein, rat;

MeSH synonym : serum and glucocorticoid-regulated kinase;

MeSH hyponym : serum-glucocorticoid regulated kinase protein, mouse; Sgk protein, mouse; serum-glucocorticoid regulated kinase 2, rat; serum-glucocorticoid regulated kinase 2, human; serum-glucocorticoid regulated kinase protein, human; SGK protein, human; serum-glucocorticoid regulated kinase protein, rat; Sgk protein, rat;

Registry Number MeSH : EC 2.7.1.37; EC 2.7.11.1;

related registry number list (CISMeF) : EC 2.7.1.37;

Is substance : O;

UNII : EC 2.7.11.1;

Details

Origin ID

C080320;

UMLS CUI

C0214539;

Automatic exact mappings (from CISMeF team)
- 3-Phosphoinositide-Dependent Protein Kinase 1 [NCIt concept]
- 5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-2 [NCIt concept]
- Activin Receptor Type-1 [NCIt concept]
- Aurora Kinase C [NCIt concept]
- Casein Kinase II Subunit Alpha [NCIt concept]
- Cell Division Cycle 7-Related Protein Kinase [NCIt concept]
- Ceramide Transfer Protein [NCIt concept]
- Cyclin-Dependent Kinase 10 [NCIt concept]
- Cyclin-Dependent Kinase 2 [NCIt concept]
- Cyclin-Dependent Kinase 3 [NCIt concept]
- Death-Associated Protein Kinase 1 [NCIt concept]
- Glycogen Synthase Kinase-3 Alpha [NCIt concept]
- LIM Domain Kinase 1 [NCIt concept]
- Leucine-Rich Repeat Serine/Threonine-Protein Kinase 2 [NCIt concept]
- MAP Kinase-Interacting Serine/Threonine-Protein Kinase 1 [NCIt concept]
- MAP Kinase-Interacting Serine/Threonine-Protein Kinase 2 [NCIt concept]
- Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 Beta [NCIt concept]
- Nik-Related Protein Kinase [NCIt concept]
- Serine/Threonine Protein Kinase [NCIt concept]
- Serine/Threonine-Protein Kinase 33 [NCIt concept]
- Serine/Threonine-Protein Kinase Nek10 [NCIt concept]
- Serine/Threonine-Protein Kinase Receptor R3 [NCIt concept]
- Transcription Initiation Factor TFIID Subunit 1 [NCIt concept]
MeSH indexing information
- nuclear proteins [MeSH Descriptor]
MeSH term(s) associated for indexing
- Protein Serine-Threonine Kinases [MeSH Descriptor]
- immediate-early proteins [MeSH Descriptor]
Record concept(s)
- SGK1 protein, human [MeSH concept]
- SGK1 protein, rat [MeSH concept]
- SGK1 protein, xenopus [MeSH concept]
- SGK2 protein, human [MeSH concept]
- Sgk1 protein, mouse [MeSH concept]
- Sgk2 protein, rat [MeSH concept]
- serum-glucocorticoid regulated kinase [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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