NCIt related terms : samarium Sm 153 lexidronam pentasodium; Quadramet;
NCIt definition : The pentasodium salt of samarium Sm 153 lexidronam, a therapeutic agent consisting
of a medium energy beta- and gamma-emitting radioisotope, samarium Sm 153, and a teraphosphonate
chelator, ethylenediaminetetramethylene phosphonic acid (EDTMP). The chelator moiety
of samarium Sm 153 lexidronam associates with hydroxyapatite crystals concentrated
in areas of bone turnover, thereby selectively delivering samarium Sm 153-mediated
cytotoxic radiation to osteoblastic bone metastases.;
Alternative definition : NCI-GLOSS: A drug used to treat pain caused by bone cancer and other cancers that
have spread to the bones. Samarium Sm 153 lexidronam pentasodium is a type of radiopharmaceutical.;
UNII : 7389YR3OOV;
InChIKey : SZZACTGRBZTAKY-NKNBZPHVSA-F;
CAS number : 160369-78-8;
Drug name : Quadramet;
Chemical formula : C6H12N2O12P4.5Na.Sm;
NSC code : 741196;
Codes from synonyms : CDR0000468775; CDR0000512828;