" /> Samarium Sm-153 Lexidronam Pentasodium - CISMeF





Preferred Label : Samarium Sm-153 Lexidronam Pentasodium;

NCIt synonyms : Samarium Sm-153 EDTMP Pentasodium; Samarium-153 EDTMP Pentasodium; Sm 153 Lexidronam Pentasodium;

NCIt related terms : samarium Sm 153 lexidronam pentasodium; Quadramet;

NCIt definition : The pentasodium salt of samarium Sm 153 lexidronam, a therapeutic agent consisting of a medium energy beta- and gamma-emitting radioisotope, samarium Sm 153, and a teraphosphonate chelator, ethylenediaminetetramethylene phosphonic acid (EDTMP). The chelator moiety of samarium Sm 153 lexidronam associates with hydroxyapatite crystals concentrated in areas of bone turnover, thereby selectively delivering samarium Sm 153-mediated cytotoxic radiation to osteoblastic bone metastases.;

Alternative definition : NCI-GLOSS: A drug used to treat pain caused by bone cancer and other cancers that have spread to the bones. Samarium Sm 153 lexidronam pentasodium is a type of radiopharmaceutical.;

UNII : 7389YR3OOV;

InChIKey : SZZACTGRBZTAKY-NKNBZPHVSA-F;

CAS number : 160369-78-8;

Drug name : Quadramet;

Chemical formula : C6H12N2O12P4.5Na.Sm;

NSC code : 741196;

Codes from synonyms : CDR0000468775; CDR0000512828;

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10/05/2025


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