RAS Guanyl-Releasing Protein 1

Preferred Label : RAS Guanyl-Releasing Protein 1;

NCIt synonyms : Ras Guanyl-Releasing Protein; Calcium and DAG-Regulated Guanine Nucleotide Exchange Factor II; CalDAG-GEFII; RASGRP1;

NCIt definition : RAS guanyl-releasing protein 1 (797 aa, 90 kDa) is encoded by the human RASGRP1 gene. This protein plays a role in the mediation of GDP-GTP exchange to regulate small GTPase signaling.;

Details

Origin ID

C97228;

UMLS CUI

C3273290;

OMIM relation
- Ras guanyl nucleotide-releasing protein 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- RASGRP1 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- RASGRP1 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_expressed_in_tissue
- Brain [NCIt concept]
gene_product_has_associated_anatomy
- T-Lymphocyte [NCIt concept]
gene_product_has_structural_domain_or_motif
- DAG/PE-Binding Domain [NCIt concept]
- EF-Hand Domain [NCIt concept]
gene_product_is_element_in_pathway
- MAPK Signaling Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD4+ T Cells [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
gene_product_plays_role_in_biological_process
- B-Cell Differentiation [NCIt concept]
- Platelet Activation [NCIt concept]
- Post-Translational Modification [NCIt concept]
- Signal Transduction [NCIt concept]
- Signal Transduction Induction [NCIt concept]
- T-Cell Differentiation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients