BTRC wt Allele

Preferred Label : BTRC wt Allele;

NCIt synonyms : FBXW1A; FWD1; FBXW1; Beta-Transducin Repeat Containing wt Allele; MGC4643; BETA-TRCP; betaTrCP; bTrCP1; FBW1A; RP11-529I10.2; bTrCP;

NCIt definition : Human BTRC wild-type allele is located in the vicinity of 10q24.32 and is approximately 204 kb in length. This allele, which encodes F-box/WD repeat-containing protein 1A, is involved in the modulation of protein ubiquitination and signal transduction.;

NCIt note : Mutations in the protein-coding region of the BTRC gene were found in multiple myeloma. (Nature. 2011; 471: 467-472.);

GenBank Accession Number : Y14153;

Details

Origin ID

C96368;

UMLS CUI

C3272739;

Automatic exact mappings (from CISMeF team)
- Beta-transducin repeat-containing protein [OMIM gene]
- beta-Transducin Repeat-Containing proteins [MeSH Descriptor]
- beta-transducin repeat containing E3 ubiquitin protein ligase [ORDO Gene]
OMIM relation
- Beta-transducin repeat-containing protein [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 10q24.32 [NCIt concept]
gene_is_element_in_pathway
- Alternative NF-kappaB Signaling Pathway [NCIt concept]
- Atypical NF-kappaB Signaling Pathway [NCIt concept]
- Beta-Catenin Accumulation Pathway [NCIt concept]
- Canonical NF-kappaB Signaling Pathway [NCIt concept]
- Circadian Rhythm Pathway KEGG [NCIt concept]
- HDAC Class I Signaling Pathway [NCIt concept]
- Hedgehog Signaling Events Mediated by Gli Family Proteins [NCIt concept]
- Hedgehog Signaling Pathway [NCIt concept]
- Notch Signaling Pathway [NCIt concept]
- Oocyte Meiosis Pathway [NCIt concept]
- Presenilin Action in Notch and Wnt Signaling Pathways [NCIt concept]
- Shigellosis Pathway [NCIt concept]
- Ubiquitin-mediated Proteolysis Pathway [NCIt concept]
- WNT Signaling Pathway BioCarta [NCIt concept]
- Wnt Signaling Pathway KEGG [NCIt concept]
gene_plays_role_in_process
- Signal Transduction [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients