MeSH definition : A family of F-box domain proteins that contain sequences that are homologous to the
beta subunit of transducin (BETA-TRANSDUCIN). They play an important role in the protein
degradation pathway by becoming components of SKP CULLIN F-BOX PROTEIN LIGASES, which
selectively act on a subset of proteins including beta-catenin and IkappaBbeta.;
A family of F-box domain proteins that contain sequences that are homologous to the
beta subunit of transducin (BETA-TRANSDUCIN). They play an important role in the protein
degradation pathway by becoming components of SKP CULLIN F-BOX PROTEIN LIGASES, which
selectively act on a subset of proteins including beta-catenin and IkappaBbeta.