Bupropion - CISMeF

Preferred Label : Bupropion;

NCIt synonyms : Amfebutamon; 1-Propanone, 1-(3-Chlorophenyl)-2-((1,1-dimethylethyl)amino)-; Bupropion Base;

NCIt definition : An aminoketone with antidepressant activity. The molecular mechanism of the antidepressant effect of bupropion is unknown. This agent does not inhibit monoamine oxidase and, compared to classical tricyclic antidepressants, is a weak blocker of the neuronal uptake of serotonin and norepinephrine. Buproprion also weakly inhibits the neuronal re-uptake of dopamine.;

Alternative definition : NCI-GLOSS: A substance that is used to treat depression, and to help people quit smoking. It belongs to the family of drugs called antidepressants.;

UNII : 01ZG3TPX31;

InChIKey : SNPPWIUOZRMYNY-UHFFFAOYSA-N;

CAS number : 34911-55-2;

Chemical formula : C13H18ClNO;

ChEBI ID : CHEBI:3219;

Codes from synonyms : CDR0000045082;

Details

Origin ID

C62012;

UMLS CUI

C0085208;

Automatic exact mappings (from CISMeF team)
- Amfebutamone [ICHI extension code]
Currated CISMeF NLP mapping
- Amfebutamone [ICD-11 Extension code]
- Bupropion [ICD-11 Extension code]
- Bupropion [ICHI extension code]
- Bupropion [SMS substance]
- Bupropion (substance) [SNOMED CT concept]
- buPROPion [LOINC component]
- bupropion [MeSH Descriptor]
- bupropion [MeSH concept]
- bupropion [SNOMED Notion]
See also inter- (CISMeF)
- Product containing bupropion (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Bupropion [ICD-11 Extension code]
- Bupropion (substance) [SNOMED CT concept]
- Product containing bupropion (medicinal product) [SNOMED CT concept]
- buPROPion [LOINC component]
- bupropion [ATC Code]
- bupropion [MeSH concept]
- bupropion [MeSH Descriptor]
- bupropion [SNOMED Notion]
Validated automatic mappings to BTNT
- bupropion [ATC Code]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 2B6 [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Bupropion Hydrobromide [NCIt concept]
- Bupropion Hydrochloride [NCIt concept]
- Bupropion Hydrochloride Controlled-release [NCIt concept]
is_free_acid_or_base_form_of
- Bupropion Hydrobromide [NCIt concept]
- Bupropion Hydrochloride [NCIt concept]
- Bupropion Hydrochloride Controlled-release [NCIt concept]

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