Bupropion Hydrochloride

Preferred Label : Bupropion Hydrochloride;

NCIt synonyms : ( -)-1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone Hydrochloride; Amfebutamone; Bupropion;

NCIt definition : The hydrochloride salt of the aminoketone bupropion, with antidepressant activity and for potential use in promoting smoking cessation and improving sexual desire. Bupropion is a weak blocker of the neuronal uptake of serotonin, dopamine and norepinephrine and is a central nicotinic acetylcholine receptor antagonist.;

UNII : ZG7E5POY8O;

InChIKey : HEYVINCGKDONRU-UHFFFAOYSA-N;

CAS number : 31677-93-7;

Drug name : Wellbutrin;

Molecule name : BW 323U66;

Chemical formula : C13H18ClNO.HCl;

NSC code : 315851;

Codes from synonyms : 20516;

Details

Origin ID

C1317;

UMLS CUI

C0700563;

Automatic exact mappings (from CISMeF team)
- Amfebutamone [ICHI extension code]
- Bupropion [ICHI extension code]
See also inter- (CISMeF)
- Bupropion hydrochloride (product) [Inactive SNOMED CT concept]
- Product containing bupropion (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to NTBT
- Amfebutamone [ICD-11 Extension code]
- Bupropion [ICD-11 Extension code]
- Bupropion [SMS substance]
- Bupropion (substance) [SNOMED CT concept]
- buPROPion [LOINC component]
- bupropion [MeSH Descriptor]
- bupropion [ATC Code]
- bupropion [MeSH concept]
- bupropion [SNOMED Notion]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 2B6 [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Bupropion [NCIt concept]
is_component_of_chemotherapy_regimen
- Bupropion/Nicotine [NCIt concept]
is_salt_form_of
- Bupropion [NCIt concept]

Keyword's position in hierarchy(ies) :

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