bupropion - CISMeF

Preferred Label : bupropion;

MeSH definition : A unicyclic, aminoketone antidepressant. The mechanism of its therapeutic actions is not well understood, but it does appear to block dopamine uptake. The hydrochloride is available as an aid to smoking cessation treatment.; A propiophenone-derived antidepressant and antismoking agent that inhibits the uptake of DOPAMINE.;

MeSH synonym : ( -)-1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone; amfebutamone;

CISMeF synonym : 34841-36-6 (Bupropion hydrochloride); GlaxoSmithKline brand 2 of bupropion hydrochloride; glaxo wellcome brand 2 of bupropion hydrochloride; GlaxoSmithKline brand 1 of bupropion hydrochloride; glaxo wellcome brand 1 of bupropion hydrochloride; glaxo wellcome brand 3 of bupropion hydrochloride; esteve brand of bupropion hydrochloride;

MeSH hyponym : wellbutrin; zyntabac; zyban (Anti-Smoking); quomen; Bupropion Hydrochloride, ( -)-Isomer; bupropion hydrochloride; Zyban (Bupropion);

Related MeSH term : bupropion, ( -)-Isomer;

MeSH CAS label : 1-Propanone, 1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-;

MeSH Related Number : bupropion hydrochloride, ( -)-Isomer; bupropion, ( -)-Isomer; bupropion hydrochloride; 31677-93-7 (HCl( -)-isomer); 34841-36-6 (HCl); 34841-39-9 (Bupropion); 34911-55-2 (( -)-isomer); ZG7E5POY8O;

Registry Number MeSH : 34841-39-9;

Related CAS MeSH : 31677-93-7 (Bupropion hydrochloride, ( -)-Isomer); 34911-55-2 (Bupropion, ( -)-Isomer); ZG7E5POY8O (Bupropion hydrochloride);

MeSH annotation : do not confuse with Zyban fungicide;

Wikipedia link : https://en.wikipedia.org/wiki/Bupropion;

Codes EINECS : 252-243-9;

Is substance : O;

UNII : 01ZG3TPX31;

InChIKey : SNPPWIUOZRMYNY-UHFFFAOYSA-N;

Details

Origin ID

D016642;

UMLS CUI

C0085208;

ATC code(s)
- bupropion [ATC Code]
- bupropion and dextromethorphan [ATC Code]
- bupropion and naltrexone [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- (+-)-2-(tert-butylamino)-3'-chloropropiophenone hydrochloride [Substance BNPC]
- Amfebutamone [ICHI extension code]
- Bupropion [PCS menu]
- Bupropion [PCS menu]
- Bupropion [ICHI extension code]
CISMeF manual mappings
- Adverse reaction caused by bupropion (disorder) [SNOMED CT concept]
- Bupropion measurement (procedure) [SNOMED CT concept]
Pharmacological action(s)
- Cytochrome P-450 CYP2D6 Inhibitors [MeSH Descriptor]
- Smoking Cessation Agents [MeSH Descriptor]
- antidepressive agents, second-generation [MeSH Descriptor]
- dopamine uptake inhibitors [MeSH Descriptor]
Record concept(s)
- Bupropion Hydrochloride, (+-)-Isomer [MeSH concept]
- bupropion [MeSH concept]
- bupropion hydrochloride [MeSH concept]
- bupropion, (+-)-Isomer [MeSH concept]
- quomen [MeSH concept]
- wellbutrin [MeSH concept]
- zyban (Anti-Smoking) [MeSH concept]
- zyntabac [MeSH concept]
Related MeSH Supplementary Concept(s)
- 2-(N-tert-butylamino)-3'-iodo-4'-azidopropiophenone [MeSH Supplementary Concept]
- BW 306U [MeSH Supplementary Concept]
- Naltrexone-Bupropion combination [MeSH Supplementary Concept]
- bupropion hydrochloride, naltrexone hydrochoride drug combination [MeSH Supplementary Concept]
- hydrobupropion [MeSH Supplementary Concept]
- hydroxybupropion [MeSH Supplementary Concept]
- radafaxine [MeSH Supplementary Concept]
See also
- smoking cessation [MeSH Descriptor]
See also inter- (CISMeF)
- (+-)-2-(tert-butylamino)-3'-chloropropiophenone hydrochloride [Substance BNPC]
- Bupropion hydrochloride (product) [Inactive SNOMED CT concept]
- Product containing bupropion (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Bupropion [ICD-11 Extension code]
- Bupropion [NCIt concept]
- Bupropion (substance) [SNOMED CT concept]
- Product containing bupropion (medicinal product) [SNOMED CT concept]
- buPROPion [LOINC component]
- bupropion [ATC Code]
- bupropion [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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