" /> Bupropion Hydrochloride Controlled-release - CISMeF





Preferred Label : Bupropion Hydrochloride Controlled-release;

NCIt synonyms : Bupropion HCl Controlled-release; Bupropion Hydrochloride Extended-Release; Bupropion HCl Extended Release;

NCIt related terms : Zyban;

NCIt definition : A controlled-release tablet formulation containing the hydrochloride salt of the aminoketone bupropion, with antidepressant activity and for potential use in promoting smoking cessation, improving sexual desire, and improving cancer-related fatigue. Bupropion is a weak blocker of the neuronal uptake of serotonin, dopamine and norepinephrine and is a central nicotinic acetylcholine receptor antagonist. Bupropion may also reduce circulating levels of tumor necrosis factor (TNF) and normalize hypothalamic-pituitary-adrenal (HPA) axis functioning, which is dysregulated in certain cases of cancer-related fatigue. The controlled-release formulation results in a higher concentration of the drug in the body over an extended period, thereby permitting a reduction in the frequency of dosing.;

Drug name : Forfivo XL; Wellbutrin XL; Wellbutrin SR; Zyban;

NCI Metathesaurus CUI : CL550923;

Codes from synonyms : NSC0170811;

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15/05/2024


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