Bupropion Hydrobromide

Preferred Label : Bupropion Hydrobromide;

NCIt synonyms : 1-Propanone, 1-(3-Chlorophenyl)-2-((1,1-dimethylethyl)amino)-, Hydrobromide;

NCIt definition : The hydrobromide salt of an aminoketone with antidepressant activity. The molecular mechanism of the antidepressant effect of bupropion is unknown. This agent does not inhibit monoamine oxidase and, compared to classical tricyclic antidepressants, is a weak blocker of the neuronal uptake of serotonin and norepinephrine. Buproprion also weakly inhibits the neuronal re-uptake of dopamine.;

UNII : E70G3G5863;

InChIKey : WSTCENNATOVXKQ-UHFFFAOYSA-N;

CAS number : 905818-69-1;

Drug name : Aplenzin;

Chemical formula : C13H18ClNO.BrH;

Details

Origin ID

C74947;

UMLS CUI

C2316497;

Currated CISMeF NLP mapping
- Bupropion hydrobromide [SMS substance]
- Bupropion hydrobromide (substance) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Bupropion hydrobromide (substance) [SNOMED CT concept]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 2B6 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Bupropion [NCIt concept]
is_salt_form_of
- Bupropion [NCIt concept]

Keyword's position in hierarchy(ies) :

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