Preferred Label : BRCA1 wt Allele;
NCIt synonyms : Breast Cancer 1, Early Onset wt Allele; PSCP; Breast Cancer 1 Gene; BRCAI; RNF53; Breast Cancer Type 1 Susceptibility Gene; PNCA4; PPP1R53; Hereditary Breast Cancer 1 Gene; IRIS; BROVCA1; FANCS; BRCC1; BRCA1, DNA Repair Associated wt Allele;
NCIt related terms : BRCA1;
NCIt definition : Human BRCA1 wild-type allele is located within 17q21 and is approximately 81 kb in
length. This allele, which encodes breast cancer type 1 susceptibility protein, plays
a role in transcriptional regulation, facilitation of the cellular response to DNA
damage, homologous recombination, and cell cycle arrest following radiation exposure.
Certain allelic variants of the BRCA1 gene are associated with breast carcinomas and
breast/ovarian cancer syndrome.;
Alternative definition : NCI-GLOSS: A gene on chromosome 17 that normally helps to suppress cell growth. A
person who inherits certain mutations (changes) in a BRCA1 gene has a higher risk
of getting breast, ovarian, prostate, and other types of cancer.;
NCIt note : The BRCA1 gene is a tumor suppressor gene. It has been shown to be involved in transcription-coupled
repair of oxidative DNA damage.;
GenBank Accession Number : NM_007294;
Codes from synonyms : CDR0000046047;
Origin ID : C52060;
UMLS CUI : C1704743;
- OMIM relation
- See also inter- (CISMeF)
- Semantic type(s)
- concept_is_in_subset
- gene_found_in_organism
- gene_has_abnormality
- gene_has_physical_location
- gene_in_chromosomal_location
- gene_involved_in_pathogenesis_of_disease
- gene_is_element_in_pathway
- gene_plays_role_in_process
https://sesstim.univ-amu.fr/fr/video-box/seminaire-interne-luka-canton-pierre-schalkwijk
2023
France
audiovisual aids
COVID-19
TNFAIP3-Interacting Protein 1
scales
Evaluation
Murine Iris
iris
epidemics
evaluation studies as topic
Projection
Physical Examination
COVID-19 Infection
Assessment
ladder, nos
weights and measures
Assessment
TNIP1 wt Allele
Epidemic Disorder
Iris
French Catheter Gauge
Projected
BRCA1 wt Allele
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