PPP2R1B wt Allele

Preferred Label : PPP2R1B wt Allele;

NCIt synonyms : Protein Phosphatase 2 (Formerly 2A), Regulatory Subunit A (PR 65), Beta Isoform wt Allele;

NCIt definition : Human PPP2R1B wild-type allele is located in the vicinity of 11q23.2 and is approximately 40 kb in length. This allele, which encodes serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform protein, plays a role in coordinating the assembly of the protein phosphatase 2A heterodimer. Functional PPP2R1B gene polymorphisms are associated with lung cancer.;

GenBank Accession Number : NM_002716;

Details

Origin ID

C49437;

UMLS CUI

C1709422;

OMIM relation
- Protein phosphatase 2, structural/regulatory subunit a, beta [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_associated_with_disease
- Lung Carcinoma [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 11q23 [NCIt concept]
gene_plays_role_in_process
- Cell Proliferation Regulatory Process [NCIt concept]
- DNA Replication [NCIt concept]
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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