" /> Melanocyte Protein PMEL - CISMeF





Preferred Label : Melanocyte Protein PMEL;

NCIt synonyms : SIL; ME20-M/ME20-S; gp100; Silver Like; ME20M/ME20S; Silver Locus Protein Homolog; SILV; Melanoma-Associated ME20 Antigen; Melanocyte Protein MEL17; ME20M; SI; ME20-M; PMEL17; ME20; Melanocyte Protein PMEL17; Silver Homolog; 95 kDa Melanocyte-Specific Secreted Glycoprotein; Melanocyte Lineage-Specific Antigen gp100; Premelanosome Protein; Melanocyte Protein Pmel 17; Melanocyte Protein 17; P1; Melanocytes Lineage-Specific Antigen gp100; P100; PMEL; Melanocyte Lineage-Specific Antigen-gp100; Melanocyte Protein Mel 17; Melanosomal Matrix Protein17;

NCIt definition : Melanocyte protein PMEL (661 aa, 70 kDa) is encoded by the human PMEL gene. This protein plays a role in melanogenesis.;

NCIt note : Melanocyte protein PMEL can be glycosylated and cleaved forming a disulfide linked dimer comprised of a large lumenal subunit, M-alpha (ME20-S; 95 kDa melanocyte-specific secreted glycoprotein; P26; secreted melanoma-associated ME20 antigen; ME20-S; ME20S) and an integral membrane subunit, M-beta. A fraction of the M-alpha is secreted and can be further processed. (UniProt);

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16/05/2024


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