gp100:154-162 Peptide Vaccine

Preferred Label : gp100:154-162 Peptide Vaccine;

NCIt synonyms : gp100:154-162 Peptide; gp100 154-162 Peptide;

NCIt definition : A peptide consisting of amino acid residues 154 through 162 of the melanoma-melanocyte antigen gp100. Vaccination with gp100:154-162 peptide may enhance tumor-specific T-cell immunity. gp100 antigen is a self-antigen expressed by melanocytes, pigmented retinal cells, and most melanoma lesions and is recognized via class I and II HLA-restricted mechanisms.;

NCI Metathesaurus CUI : CL053051;

NSC code : 676540;

Details

Origin ID

C2764;

UMLS CUI

C1515629;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_abnormal_cell
- Melanoma Cell [NCIt concept]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
concept_is_in_subset
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Melanocyte Protein PMEL [NCIt concept]

Keyword's position in hierarchy(ies) :

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