Autologous Anti-gp100:154-162 TCR Tumor Infiltrating Lymphocytes

Preferred Label : Autologous Anti-gp100:154-162 TCR Tumor Infiltrating Lymphocytes;

NCIt synonyms : Autologous Anti-gp100:154-162 TCR Gene-engineered Tumor Infiltrating Lymphocytes; Autologous Anti-gp100:154-162 TCR TILs; Autologous Anti-gp100:154-162 TCR-engineered TILs; Autologous Anti-gp100:154-162 TCR Gene Engineered TILs; Autologous Anti-gp 100:154-162 TCR TILs;

NCIt definition : A preparation of human tumor infiltrating lymphocytes (TILs) isolated from a melanoma patient and engineered to encode a T-cell receptor (TCR) specific for the amino acid 154 through 162 of the melanoma antigen glycoprotein 100 (gp100), with potential immunomodulating and antineoplastic activities. Upon intravenous administration, the autologous anti-gp100:154-162 TCR TILs may recognize and halt the growth of gp100-expressing melanoma cells.;

NCI Metathesaurus CUI : CL1663069;

Details

Origin ID

C180517;

UMLS CUI

C5556435;

Semantic type(s)
- Cell [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Melanocyte Protein PMEL [NCIt concept]

Keyword's position in hierarchy(ies) :

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