gp100:280-288 Peptide Vaccine

Preferred Label : gp100:280-288 Peptide Vaccine;

NCIt synonyms : gp100:280-288 Peptide; gP100 Peptide Melanoma Vaccine YLEPGPVTA; gp100 280-288 Peptide;

NCIt definition : A vaccine consisting of the amino acids 280 through 288 of the melanoma antigen glycoprotein 100 (gp100) with potential antineoplastic activity. Vaccination with gp100:280-288 peptide may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the gp100 antigen, resulting in decreased tumor growth. (NCI04);

NSC code : 676539;

Details

Origin ID

C2767;

UMLS CUI

C1515632;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_abnormal_cell
- Melanoma Cell [NCIt concept]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
concept_is_in_subset
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Melanocyte Protein PMEL [NCIt concept]

Keyword's position in hierarchy(ies) :

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