Recombinant Fowlpox-gp100p209

Preferred Label : Recombinant Fowlpox-gp100p209;

NCIt synonyms : rF-gp100p209;

NCIt definition : A viral vaccine comprised of a recombinant fowlpox vector construct encoding a modified epitope of the melanoma antigen glycoprotein 100 (gp100), ES-2092M(gp100), containing an endoplasmic reticulum signal sequence targeted to the endoplasmic reticulum apparatus. Vaccination with recombinant fowlpox-gp100p209 vaccine may stimulate the host immune system more efficiently to mount a cytotoxic T lymphocyte response against tumor cells expressing the gp100 antigen.;

NSC code : 702139;

Details

Origin ID

C2806;

UMLS CUI

C1514778;

Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Gene Regulation Process [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
has_target
- Melanocyte Protein PMEL [NCIt concept]

Keyword's position in hierarchy(ies) :

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