Serine/Threonine-Protein Phosphatase 2A Regulatory Subunit B'' Subunit Beta

Preferred Label : Serine/Threonine-Protein Phosphatase 2A Regulatory Subunit B'' Subunit Beta;

NCIt synonyms : PP2A B Double Prime Subunit PR48; Protein Phosphatase 2A 48 kDa Regulatory Subunit; PP2A Subunit B PR48 Isoform; NY-REN-8 Antigen; NY-REN-8; PR48; Serine/Threonine Protein Phosphatase 2A 48kDa Regulatory Subunit; Serine/Threonine Protein Phosphatase 2A 48kDa Regulatory Subunit B; Protein Phosphatase-2A-48kDa Regulatory Subunit; B Double Prime; Serine/Threonine-Protein Phosphatase 2A Regulatory Subunit B Double Prime Subunit Beta; PPP2R3B;

NCIt definition : Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta (575 aa, 65 kDa) is encoded by the human PPP2R3B gene. This protein may be involved in the localization, substrate specificity and the modulation of activity for protein phosphatase 2A.;

NCIt note : Protein Phosphatase 2A 48kDa Regulatory Subunit is a B regulatory subunit of PP2A. PR48 specifically interacts with the N-terminal region of and dephosphorylates CDC6, modulating initiation of DNA replication and cell cycle control.;

Details

Origin ID

C37317;

UMLS CUI

C1438728;

OMIM relation
- Protein phosphatase 2, regulatory subunit b-double prime, beta [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PPP2R3B protein, human [MeSH Supplementary Concept]
- PPP2R3B protein, human [MeSH concept]
gene_encodes_gene_product
- PPP2R3B Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_is_element_in_pathway
- AKAP8 in Mitosis Pathway [NCIt concept]
- AKT Signaling Pathway [NCIt concept]
- Alzheimer's Disease Pathway BioCarta [NCIt concept]
- Beta-Catenin Accumulation Pathway [NCIt concept]
- CK1/CDK5 Regulation Pathway [NCIt concept]
- CTCF Pathway [NCIt concept]
- Centrosome Pathway [NCIt concept]
- ChREBP Pathway [NCIt concept]
- Erk1/Erk2 MAPK Signaling Pathway [NCIt concept]
- Keratinocyte Differentiation Pathway [NCIt concept]
- Skeletal Muscle Hypertrophy Pathway [NCIt concept]
- Telomere Pathway [NCIt concept]
- WNT Signaling Pathway BioCarta [NCIt concept]
- mTOR Signaling Pathway BioCarta [NCIt concept]
gene_product_is_physical_part_of
- Protein Phosphatase 2A [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Cycle Regulation Process [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Replication Initiation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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