Interleukin-12 Subunit Alpha

Preferred Label : Interleukin-12 Subunit Alpha;

NCIt synonyms : IL-12A; Interleukin 12A Precursor; NFSK; Cytotoxic Lymphocyte Maturation Factor; Interleukin-12 Alpha Chain; CLMF; Interleukin-12 Alpha Chain Precursor; Interleukin 12A; NF Cell Stimulatory Factor Chain 1; interleukin 12, p35; Natural Killer Cell Stimulatory Factor, 35-kD Subunit; IL-12, subunit p35; IL12, Subunit P35; Cytotoxic Lymphocyte Maturation Factor 35 kDa Subunit; NKSF1; CLMF p35; Interleukin 12A (Natural Killer Cell Stimulatory Factor 1, Cytotoxic Lymphocyte Maturation Factor 1, p35); Natural Killer Cell Stimulatory Factor 1, 35 kD Subunit; IL12A Protein; Cytotoxic Lymphocyte Maturation Factor 1, p35; IL12A; Interleukin-12A; IL12 Subunit P35; IL35 Subunit A; Natural Killer Cell Stimulatory Factor, 35 kD Subunit;

NCIt definition : Interleukin-12 subunit alpha (219 aa, 25 kDa) is encoded by the human IL12A gene. This protein plays a role in cytokine signaling in both T-cells and natural killer cells.;

NCIt note : Interleukin-12 subunit alpha forms a heterodimer with interleukin-12 subunit beta called interleukin-12.;

Details

Origin ID

C28508;

UMLS CUI

C1701815;

Currated CISMeF NLP mapping
- Interleukin-12A [FMA entity]
OMIM relation
- Interleukin 12a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- IL12A protein, human [MeSH concept]
- IL12A protein, human [MeSH Supplementary Concept]
- Interleukin-12 subunit p35 [MeSH concept]
- Interleukin-12A [FMA entity]
- interleukin-12 subunit p35 [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Gene [NCIt concept]
- IL12A Gene [NCIt concept]
- Interleukin Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Protein Complex Subunit [NCIt concept]
- Signaling Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Allograft Rejection Pathway [NCIt concept]
- Amoebiasis Pathway [NCIt concept]
- Chagas Disease Pathway [NCIt concept]
- Cytokine Network Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Dendritic Cell Pathway [NCIt concept]
- IL12 Signaling Pathway [NCIt concept]
- IL12-Mediated Signaling Pathway [NCIt concept]
- IL18 Signaling Pathway [NCIt concept]
- IL27-Mediated Signaling Pathway [NCIt concept]
- Inflammatory Response Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- Leishmaniasis Infection Pathway [NCIt concept]
- Malaria Pathway [NCIt concept]
- NO2-Dependent IL12 Pathway [NCIt concept]
- RIG-I-Like Receptor Signaling Pathway [NCIt concept]
- T-Cell Polarization Pathway [NCIt concept]
- Th1/Th2 Differentiation Pathway [NCIt concept]
- Toll-Like Receptor Signaling Pathway [NCIt concept]
- Type I Diabetes Mellitus Pathway [NCIt concept]
gene_product_is_physical_part_of
- Interleukin-12 [NCIt concept]
- Interleukin-35 [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Cell-Mediated Immunity [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
- NK Cell Activation [NCIt concept]
- T-Cell Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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