" /> Transcription Factor Sp1 - CISMeF





Preferred Label : Transcription Factor Sp1;

NCIt synonyms : SP1; Stimulatory Protein 1; Sp1 Transcription Factor;

NCIt definition : Transcription factor Sp1 (785 aa, 80 kDa) is encoded by the human SP1 gene. This protein plays a role in the regulation of gene expression.;

NCIt note : Transcription factor SP1 is a DNA-binding protein that interacts with various RNA polymerase II gene promoters containing GC-box elements. It has contiguous zinc finger motifs and requires zinc for sequence-specific binding to DNA. The formation of head segments in Drosophila depends on the homologue of the human transcription factor SP1. (from OMIM 189906);

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30/07/2025


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