sp1 transcription factor

Preferred Label : sp1 transcription factor;

MeSH definition : Promoter-specific RNA polymerase II transcription factor that binds to the GC box, one of the upstream promoter elements, in mammalian cells. The binding of Sp1 is necessary for the initiation of transcription in the promoters of a variety of cellular and viral GENES.;

MeSH synonym : transcription factor, sp1; specificity protein 1 transcription factor;

MeSH annotation : /drug eff /ultrastruct permitted; in titles & translations use SP1 (the figure one), not SPl (the letter l);

Wikipedia link : https://en.wikipedia.org/wiki/Sp1 transcription factor;

Is substance : O;

Details

Origin ID

D016329;

UMLS CUI

C0080245;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Transcription Factor Sp1 [NCIt concept]
Record concept(s)
- Sp1 transcription factor [MeSH concept]
Related MeSH Supplementary Concept(s)
- Sp1 protein, drosophila [MeSH Supplementary Concept]
- Sp1 protein, human [MeSH Supplementary Concept]
- Sp1 protein, rat [MeSH Supplementary Concept]
- splase [MeSH Supplementary Concept]
See also
- HIV long terminal repeat [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Transcription Factor Sp1 [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients