Preferred Label : HIV long terminal repeat;
MeSH definition : Regulatory sequences important for viral replication that are located on each end
of the HIV genome. The LTR includes the HIV ENHANCER, promoter, and other sequences.
Specific regions in the LTR include the negative regulatory element (NRE), NF-kappa
B binding sites , Sp1 binding sites, TATA BOX, and trans-acting responsive element
(TAR). The binding of both cellular and viral proteins to these regions regulates
HIV transcription.;
MeSH synonym : human immunodeficiency virus ltr; ltr, human immunodeficiency virus; long terminal repeat, hiv; human immunodeficiency virus long terminal repeat;
MeSH hyponym : Sp1-Binding site, HIV; HIV-1 LTR; negative regulatory element, HIV; Trans-Acting responsive region, HIV; Trans Acting Responsive Region, HIV; HIV Trans-Acting Responsive Region; HIV Trans Acting Responsive Region; Trans-Activation Responsive Element, HIV; Trans Activation Responsive Element, HIV; Trans-Activation Responsive Region, HIV; Trans Activation Responsive Region, HIV; TAR Element, HIV; HIV TAR Element; HIV TAR Elements; TAR Elements, HIV; Sp1 Binding Site, HIV; HIV Sp1-Binding Site; HIV Sp1 Binding Site; HIV Sp1-Binding Sites; Sp1-Binding Sites, HIV; HIV 1 LTR; LTR, HIV-1; HIV Negative Regulatory Element;
MeSH annotation : DF: HIV LTR or HIV TAR;
Is substance : O;
Origin ID : D016325;
UMLS CUI : C0079517;
Allowable qualifiers
- Record concept(s)
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Regulatory sequences important for viral replication that are located on each end
of the HIV genome. The LTR includes the HIV ENHANCER, promoter, and other sequences.
Specific regions in the LTR include the negative regulatory element (NRE), NF-kappa
B binding sites , Sp1 binding sites, TATA BOX, and trans-acting responsive element
(TAR). The binding of both cellular and viral proteins to these regions regulates
HIV transcription.
