splase - CISMeF

Preferred Label : splase;

MeSH note : constructed by genetically fusing the DNA-cleavage domain of FokI restriction endonuclease with the zinc-finger DNA-binding domain of transcription factor Sp1; recognizes a 10-bp sequence of the long terminal repeat of HIV-1 DNA at Sp1 sites and cleaves phosphodiester bonds upstream of thebinding sequence;

Registry Number MeSH : EC 3.1.21.-;

Is substance : O;

Details

Origin ID

C104571;

UMLS CUI

C0536190;

MeSH term(s) associated for indexing
- deoxyribonucleases, type ii site-specific [MeSH Descriptor]
- sp1 transcription factor [MeSH Descriptor]
Record concept(s)
- splase [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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