Preferred Label : deoxyribonucleases, type ii site-specific;
MeSH definition : Enzyme systems containing a single subunit and requiring only magnesium for endonucleolytic
activity. The corresponding modification methylases are separate enzymes. The systems
recognize specific short DNA sequences and cleave either within, or at a short specific
distance from, the recognition sequence to give specific double-stranded fragments
with terminal 5'-phosphates. Enzymes from different microorganisms with the same specificity
are called isoschizomers. EC 3.1.21.4.;
MeSH synonym : site-specific dnase, type ii; type ii site specific dnase; type ii site-specific deoxyribonucleases; dna restriction enzymes, type ii; dnase, site specific, type ii; restriction endonucleases, type ii; type ii site-specific dnase; type ii site specific deoxyribonucleases; type ii restriction enzymes; site specific dnase, type ii; dnase, site-specific, type ii; deoxyribonucleases, type II site specific; deoxyribonucleases, type II, Site-Specific; deoxyribonucleases, type II, site specific;
Registry Number MeSH : EC 3.1.21.4;
MeSH annotation : a DNA restriction enzyme; DF: DNASE SS II;
Wikipedia link : https://en.wikipedia.org/wiki/Deoxyribonucleases, type ii site-specific;
Is substance : O;
UNII : EC 3.1.21.4;
Origin ID : D015252;
UMLS CUI : C0011524;
Allowable qualifiers
Automatic exact mappings (from CISMeF team)
Record concept(s)
Related MeSH Supplementary Concept(s)
- splase [MeSH Supplementary Concept]
Semantic type(s)
UMLS correspondences (same concept)
Enzyme systems containing a single subunit and requiring only magnesium for endonucleolytic
activity. The corresponding modification methylases are separate enzymes. The systems
recognize specific short DNA sequences and cleave either within, or at a short specific
distance from, the recognition sequence to give specific double-stranded fragments
with terminal 5'-phosphates. Enzymes from different microorganisms with the same specificity
are called isoschizomers. EC 3.1.21.4.