Guanine Nucleotide-Binding Protein G(s) Subunit Alpha Isoforms XLas

Preferred Label : Guanine Nucleotide-Binding Protein G(s) Subunit Alpha Isoforms XLas;

NCIt synonyms : G(s) Alpha; GNAS; G-s Alpha; Extra Large Alphas Protein; XLalphas; Guanine Nucleotide Binding Protein G(s) Subunit Alpha Isoforms XLas; Adenylate Cyclase-Stimulating G Alpha Protein;

NCIt definition : Guanine nucleotide-binding protein G(s), subunit alpha isoforms XLas (1037 aa, 111 kDa) is encoded by the human GNAS gene. This protein may play a role in signal transduction by activating adenylate cyclase in response to beta-adrenergic stimuli.;

Details

Origin ID

C17983;

UMLS CUI

C2703069;

Automatic exact mappings (from CISMeF team)
- GNAS complex locus [ORDO Gene]
- GTP-Binding protein alpha subunits, gs [MeSH Descriptor]
- GTP-Binding protein alpha subunits, gs [MeSH concept]
- Gnas complex locus [OMIM Phenotype]
- Gnas complex locus [OMIM gene]
OMIM relation
- Gnas complex locus [OMIM Phenotype]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- GNAS Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_biochemical_function
- GTPase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Coiled-Coil Domain [NCIt concept]
gene_product_is_element_in_pathway
- Attenuation of GPCR Signaling Pathway [NCIt concept]
- CCR3 Signaling Pathway [NCIt concept]
- CFTR Pathway [NCIt concept]
- CREB Activation Signaling Pathway [NCIt concept]
- CSK Protein Kinase Activation Pathway [NCIt concept]
- ChREBP Pathway [NCIt concept]
- Corticosteroid Cardioprotection Pathway [NCIt concept]
- Erk1/Erk2 MAPK Signaling Pathway [NCIt concept]
- G-Protein Signaling Pathway [NCIt concept]
- GPCR Desensitization Pathway [NCIt concept]
- GPCR Signaling Pathway [NCIt concept]
- Ion Channels in Vascular Endothelium Pathway [NCIt concept]
- MAP Kinase Activation Pathway [NCIt concept]
- Oocyte Maturation Pathway [NCIt concept]
- Phospholipase C-Epsilon Signaling Pathway [NCIt concept]
- Protein Kinase A Activation Pathway [NCIt concept]
- Spermatogenesis Regulation Pathway [NCIt concept]
gene_product_is_physical_part_of
- Heterotrimeric G Protein [NCIt concept]
gene_product_plays_role_in_biological_process
- Environment-to-Cell Communication [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- GTP Binding [NCIt concept]
- Hydrolysis [NCIt concept]
- Ligand Binding [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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