Preferred Label : protein C;

MeSH definition : A vitamin-K dependent zymogen present in the blood, which, upon activation by thrombin and thrombomodulin exerts anticoagulant properties by inactivating factors Va and VIIIa at the rate-limiting steps of thrombin formation.;

Is substance : O;

Details


Main resources

You can consult :

A vitamin-K dependent zymogen present in the blood, which, upon activation by thrombin and thrombomodulin exerts anticoagulant properties by inactivating factors Va and VIIIa at the rate-limiting steps of thrombin formation.

https://www.has-sante.fr/jcms/p_3456312/fr/ceprotin-proteine-c-humaine-deficit-congenital-severe-en-proteine-c
2023
false
false
false
France
protein C
treatment outcome
insurance, health, reimbursement
protein c
protein c deficiency
Coumarin necrosis (disorder)
purpura fulminans
venous thrombosis
evaluation of the transparency committee
protein c deficiency

---
http://www.has-sante.fr/portail/jcms/c_2634439/fr/octaplex
2016
false
France
French
evaluation of the transparency committee
treatment outcome
blood coagulation factors
prothrombin complex concentrates
injections, intravenous
drug combinations
factor VII
factor IX
coagulation factor ix, ii, vii and x in combination
prothrombin
factor X
blood loss, surgical
blood loss, surgical
coagulation protein disorders
protein C
protein S

---
https://tel.archives-ouvertes.fr/tel-01220590
2015
false
false
false
France
French
dissertations, academic
protein c, nos
neoplasm, malignant
natural
anticoagulants
cancer
thrombosis
thrombus, nos
role
association
anticoagulant, nos
protein C
neoplasms

---
https://ansm.sante.fr/uploads/2021/03/12/901e9c291a545dff52c0b41365c0d6e2.pdf
2014
false
France
French
embolism and thrombosis
embolism and thrombosis
drug information
reports and studies
guidelines for drug use
Factor Xa Inhibitors
anticoagulotherapy
Dabigatran
Rivaroxaban
phenindione
pipecolic acids
dermatan sulfate
heparitin sulfate
chondroitin sulfates
hirudins
peptide fragments
recombinant proteins
heparin, low-molecular-weight
polysaccharides
pyridines
thiophenes
pyrazoles
pyridones
protein C
anticoagulants
france
drug utilization
drug utilization review
vitamin K
administration, oral
injections
heparin
direct thrombin inhibitors
heparin group
vitamin k antagonists
drug interactions
anticoagulants
hemorrhage
risk management
thrombin
factor xa
product surveillance, postmarketing
other antithrombotic agents
continuity of patient care
acenocoumarol
warfarin
fluindione
apixaban
nadroparin
dalteparin
enoxaparin
antithrombin III
argatroban
danaparoid
bivalirudin
Fondaparinux
Tinzaparin

---
http://www.has-sante.fr/portail/jcms/c_1651881/fr/confidex
http://www.has-sante.fr/portail/jcms/c_1651880/fr/confidex-02102013-avis-ct13171
2013
France
French
evaluation of the transparency committee
drug combinations
injections, intravenous
prothrombin
factor IX
factor VII
factor X
coagulation factor ix, ii, vii and x in combination
blood loss, surgical
coagulation protein disorders
blood loss, surgical
protein C
protein S

---
https://www.ema.europa.eu/medicines/human/EPAR/Xigris
2012
United Kingdom
English
French
syndication feed
adult
recombinant proteins
anti-infective agents
sepsis
protein C
treatment outcome
drug evaluation
drotrecogin alfa activated
drotrecogin alfa (activated)
protein C
recombinant proteins
drug evaluation
package leaflet
summary of product characteristics

---
http://www.cochrane.org/fr/CD005385
2012
false
true
false
United Kingdom
France
drotrecogin alfa activated
protein C
treatment outcome
review of literature
french abstract
Neonatal Sepsis
infant, newborn
protein C
recombinant proteins

---
https://www.ema.europa.eu/medicines/human/EPAR/Ceprotin
2011
false
United Kingdom
French
English
syndication feed
protein C
protein c deficiency
fibrinolytic agents
anticoagulants
protein C
fibrinolytic agents
anticoagulants
treatment outcome
drug evaluation
protein c deficiency
injections, intravenous
drug approval
drug labeling
pregnancy
breast feeding
drug compounding
adult
child
protein c
package leaflet
drug evaluation
summary of product characteristics

---
http://www.has-sante.fr/portail/jcms/c_981919/xigris
http://www.has-sante.fr/portail/upload/docs/application/pdf/2010-09/xigris_-_ct-7762.pdf
2010
France
French
drotrecogin alfa activated
infusions, intravenous
drotrecogin alfa (activated)
recombinant proteins
anti-infective agents
adult
sepsis
multiple organ failure
treatment outcome
protein C
protein C
recombinant proteins
evaluation of the transparency committee

---
http://www.has-sante.fr/portail/jcms/c_816557/confidex-complexe-prothrombique-humain-ppsb-facteurs-de-la-coagulation
http://www.has-sante.fr/portail/jcms/c_818184/synthese-d-avis-confidex-ct-6478
2009
false
France
French
drug combinations
prothrombin
factor VII
blood loss, surgical
factor IX
factor X
blood loss, surgical
coagulation protein disorders
blood coagulation factors
prothrombin complex concentrates
coagulation factor ix, ii, vii and x in combination
blood coagulation factors
protein S
protein C
guidelines for drug use
evaluation of the transparency committee

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61825519
2008
France
French
drotrecogin alfa activated
infusions, intravenous
recombinant proteins
protein C
drotrecogin alfa (activated)
drug information

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65850594
2008
France
French
drotrecogin alfa activated
infusions, intravenous
recombinant proteins
protein C
drotrecogin alfa (activated)
drug information

---
https://www.amub-ulb.be/system/files/rmb/old/496
2008
Belgium
journal article
adolescent
drug therapy
venous thrombosis
observation
protein S
antithrombin proteins
protein C
patients
fasting
muscle proteins
jeune syndrome

---
http://francais.mcgill.ca/files/tau/Final_report_Drotrecogin_alfa.pdf
2007
Canada
French
English
protein C
recombinant proteins
sepsis
fibrinolytic agents
drotrecogin alfa activated
drotrecogin alfa (activated)
protein C
recombinant proteins
french abstract
drug evaluation

---
http://www.has-sante.fr/portail/display.jsp?id=c_556247
2007
France
French
protein C
anti-infective agents
protein C
recombinant proteins
adult
sepsis
multiple organ failure
infusions, intravenous
treatment outcome
recombinant proteins
drotrecogin alfa activated
drotrecogin alfa activated
drotrecogin alfa (activated)
protein C
recombinant proteins
evaluation of the transparency committee

---
http://www.has-sante.fr/portail/display.jsp?id=c_400327
2005
France
French
evaluation of the transparency committee
blood coagulation factors
prothrombin complex concentrates
injections, intravenous
drug combinations
factor VII
factor IX
coagulation factor ix, ii, vii and x in combination
prothrombin
factor X
blood loss, surgical
blood loss, surgical
coagulation protein disorders
protein C
protein S

---
https://www.cadth.ca/sites/default/files/pdf/190_apc_cetap_e.pdf
https://www.cadth.ca/sites/default/files/pdf/190_apc_cetap_f.pdf
2002
Canada
French
English
drotrecogin alfa activated
sepsis
canada
protein C
treatment outcome
Evidence-Based medicine
adult
recombinant proteins
anti-infective agents
united states
drotrecogin alfa (activated)
protein C
recombinant proteins
drug evaluation

---
http://www.has-sante.fr/portail/display.jsp?id=c_244371
2002
France
French
protein C
recombinant proteins
anti-infective agents
adult
sepsis
drotrecogin alfa activated
drotrecogin alfa (activated)
protein C
recombinant proteins
guidelines for drug use

---
http://www.has-sante.fr/portail/display.jsp?id=c_399767
2002
France
French
drotrecogin alfa activated
recombinant proteins
protein C
anti-infective agents
sepsis
infusions, intravenous
adult
treatment outcome
insurance, health, reimbursement
multiple organ failure
drotrecogin alfa (activated)
evaluation of the transparency committee

---
http://www.has-sante.fr/portail/display.jsp?id=c_242718
2001
France
French
protein C
protein c
evaluation of the transparency committee

---
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01/05/2025


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