Protein C Concentrate

Preferred Label : Protein C Concentrate;

NCIt synonyms : Protein C (Homo sapiens);

NCIt related terms : PROTEIN C; Protein C human;

NCIt definition : A concentrate of protein C, a vitamin K-dependent, heterodimeric plasma glycoprotein and serine protease that is normally synthesized in the liver, that can be used as an anticoagulant in patients with congenital protein C deficiency. Upon intravenous administration, protein C concentrate replaces missing endogenous protein C. Protein C is converted by the thrombin/thrombomodulin-complex on the endothelial cell surface to activated Protein C (APC). APC inactivates factors Va and VIIIa, which leads to a decrease in thrombin formation. APC also has profibrinolytic effects. The protein C pathway plays an important role in the regulation of blood coagulation.;

UNII : 3Z6S89TXPW;

CAS number : 60202-16-6;

Drug name : Ceprotin; Protexel;

Codes from synonyms : 114468;

Details

Origin ID

C87607;

UMLS CUI

C0033621;

Currated CISMeF NLP mapping
- Protein C [ICD-11 Extension code]
- Protein C [SMS substance]
- Protein C [LOINC component]
- Protein C [MedDRA Preferred Term]
- Protein C (substance) [SNOMED CT concept]
- protein C [Blood Transfusion thesaurus concept]
- protein C [MeSH Descriptor]
- protein C [MeSH concept]
- protein C (synaptosomal) [MeSH concept]
- protein C (synaptosomal) [MeSH Supplementary Concept]
- protein c, nos [SNOMED Notion]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing protein C (medicinal product) [SNOMED CT concept]
- Protein C [LOINC component]
- Protein C (substance) [SNOMED CT concept]
- protein C [MeSH Descriptor]
- protein C [MeSH concept]
- protein c [ATC Code]
- protein c, nos [SNOMED Notion]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients