Double-Strand Break Repair Protein MRE11

Preferred Label : Double-Strand Break Repair Protein MRE11;

NCIt synonyms : Meiotic Recombination 11 Homolog 1; MRE11 Homolog 1; MRE11 Homolog A; Meiotic Recombination 11 Homolog A; Endo/Exonuclease Mre11; Double-Strand Break Repair Protein MRE11A; MRE11A;

NCIt definition : Double-strand break repair protein MRE11 (708 aa, 81 kDa) is encoded by the human MRE11 gene. This protein plays a role in the mediation of DNA double-strand break repair, recombination and telomere maintenance.;

Details

Origin ID

C98169;

UMLS CUI

C0674686;

OMIM relation
- Mre11 homolog, double-strand break repair nuclease [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- MRE11 protein, human [MeSH Supplementary Concept]
- MRE11 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DNA Repair Gene [NCIt concept]
- MRE11 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleoplasm [NCIt concept]
gene_product_is_element_in_pathway
- ATM Signaling Pathway [NCIt concept]
- BARD1 Signaling Pathway [NCIt concept]
- Cancer Susceptibility Pathway [NCIt concept]
- Homologous Recombination Pathway [NCIt concept]
- Non-Homologous End-Joining Pathway [NCIt concept]
- Telomerase Regulation Pathway [NCIt concept]
gene_product_is_physical_part_of
- MRE11/RAD50 Double-Strand Break Repair Complex [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- DNA Repair [NCIt concept]
- Elongation by Telomerase [NCIt concept]
- Nonhomologous DNA End Joining [NCIt concept]
- Recombination Repair [NCIt concept]

Keyword's position in hierarchy(ies) :

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