Dickkopf-Related Protein 1

Preferred Label : Dickkopf-Related Protein 1;

NCIt synonyms : Dickkopf Related Protein-1; Dkk-1; SK; Dickkopf-1; hDkk-1;

NCIt definition : Dickkopf-related protein 1 (266 aa, 29 kDa) is encoded by the human DKK1 gene. This protein is involved in both receptor binding and cell communication.;

Details

Origin ID

C95418;

UMLS CUI

C2987134;

OMIM relation
- Dickkopf wnt signaling pathway inhibitor 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DKK1 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_biochemical_function
- Signaling Protein [NCIt concept]
gene_product_is_element_in_pathway
- Beta-Catenin Accumulation Pathway [NCIt concept]
- Pitx2 Transcription Regulation Pathway [NCIt concept]
- Presenilin Action in Notch and Wnt Signaling Pathways [NCIt concept]
- Segmentation Clock Pathway [NCIt concept]
- WNT Signaling Pathway BioCarta [NCIt concept]
- Wnt Signaling Pathway KEGG [NCIt concept]
- Wnt Signaling Pathway PID [NCIt concept]
- Wnt/LRP6 Signaling Pathway [NCIt concept]
- p53 Effector Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Intercellular Communication Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Signal Transduction Inhibition [NCIt concept]
is_target
- Anti-DKK1 Monoclonal Antibody BHQ880 [NCIt concept]
- Anti-DKK1 Monoclonal Antibody JS015 [NCIt concept]
- Sirexatamab [NCIt concept]

Keyword's position in hierarchy(ies) :

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