TCF7L2 wt Allele

Preferred Label : TCF7L2 wt Allele;

NCIt synonyms : Transcription Factor 7 Like 2 wt Allele; TCF-4; TCF4; Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) Gene;

NCIt definition : Human TCF7L2 wild-type allele is located in the vicinity of 10q25.3 and is approximately 217 kb in length. This allele, which encodes transcription factor 7-like 2 protein, is involved in the Wnt protein signaling pathway. The gene may play a role in colorectal cancer development.;

GenBank Accession Number : NM_030756;

Details

Origin ID

C53105;

UMLS CUI

C1705000;

OMIM relation
- Transcription factor 7-like 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 10q25.3 [NCIt concept]
gene_is_element_in_pathway
- Acute Myeloid Leukemia Pathway [NCIt concept]
- Adherens Junction Assembly Pathway [NCIt concept]
- Arrhythmogenic Right Ventricular Cardiomyopathy Pathway [NCIt concept]
- Basal Cell Carcinoma Pathway [NCIt concept]
- Colorectal Cancer Pathway [NCIt concept]
- Endometrial Cancer Pathway [NCIt concept]
- Melanogenesis Pathway [NCIt concept]
- Papillary Thyroid Carcinoma Pathway [NCIt concept]
- Prostate Cancer Pathway [NCIt concept]
- Wnt Signaling Pathway KEGG [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]
- Signal Transduction [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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