VCL wt Allele - CISMeF

Preferred Label : VCL wt Allele;

NCIt synonyms : MVCL; Vinculin wt Allele; CMH15; CMD1W; HEL114; MV;

NCIt definition : Human VCL wild-type allele is located within 10q22.1-q23 and is approximately 122 kb in length. This allele, which encodes vinculin protein, is involved in the mediation of cellular adhesion, morphology and motility.;

NCIt note : The VCL gene product plays a role in the attachment of actin-based microfilaments to the plasma membrane. (SwissProt/GeneCards);

GenBank Accession Number : NM_003373;

Details

Origin ID

C52335;

UMLS CUI

C1705503;

OMIM relation
- Vinculin [OMIM gene]
See also inter- (CISMeF)
- Cardiomyopathy, familial hypertrophic, 15 [OMIM Phenotype]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 10q22.1-q23 [NCIt concept]
gene_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Adherens Junction Assembly Pathway [NCIt concept]
- Amoebiasis Pathway [NCIt concept]
- Bacterial Invasion of Epithelial Cell Pathway [NCIt concept]
- Cell to Cell Adhesion Signaling Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Integrin Signaling Pathway [NCIt concept]
- Leukocyte Transendothelial Migration Pathway [NCIt concept]
- Rho Cell Motility Signaling Pathway [NCIt concept]
- Shigellosis Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Adhesion Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Tumor Suppression [NCIt concept]

Keyword's position in hierarchy(ies) :

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