TLR4 wt Allele

Preferred Label : TLR4 wt Allele;

NCIt synonyms : TLR4; TOLL; hToll; Toll-Like Receptor 4 wt Allele; CD284; TOLL, Drosophila, Homolog of Gene; TLR-4; Homolog of Drosophila Toll Gene;

NCIt definition : Human TLR4 wild-type allele is located within 9q32-q33 and is approximately 11 kb in length. This allele, which encodes toll-like receptor 4 protein, is involved in pathogen recognition, signal transduction and innate immunity. Mutations in the gene are associated with differences in LPS responsiveness.;

GenBank Accession Number : NM_003266;

Details

Origin ID

C52241;

UMLS CUI

C1705581;

OMIM relation
- Toll-like receptor 4 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 9q32-q33 [NCIt concept]
gene_is_element_in_pathway
- Amoebiasis Pathway [NCIt concept]
- Beta-Catenin Accumulation Pathway [NCIt concept]
- Chagas Disease Pathway [NCIt concept]
- Dendritic Cell Pathway [NCIt concept]
- Leishmaniasis Infection Pathway [NCIt concept]
- Malaria Pathway [NCIt concept]
- NFKB Signaling Pathway [NCIt concept]
- Pathogenic Escherichia coli Infection Pathway [NCIt concept]
- Phagocytosis Pathway [NCIt concept]
- Salmonella Pathway [NCIt concept]
- Toll-Like Receptor Pathway [NCIt concept]
- Toll-Like Receptor Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Immune Response Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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