" /> CDC42 wt Allele - CISMeF





Preferred Label : CDC42 wt Allele;

NCIt synonyms : CDC42Hs; G25K; Cell Division Cycle 42 wt Allele; GP;

NCIt definition : Human CDC42 wild-type allele is located in the vicinity of 1p36.33 and is approximately 22 kb in length. This allele, which encodes PITSLRE serine/threonine-protein kinase CDC2L1 protein, is involved in signal transduction pathways that control diverse cellular functions such as: cell morphology, migration, endocytosis and cell cycle progression.;

NCIt note : ACK1 is a binding partner and inhibitor of the GTP-bound form of CDC42. Interaction between GTP-CDC42 and ACK1 inhibits both the intrinsic and GAP-stimulated GTPase activity of CDC42. Alternative splicing of the CDC42 gene results in the placental and brain isoforms.;

GenBank Accession Number : NM_001791;

Détails


Vous pouvez consulter :


Nous contacter.
31/07/2025


[Accueil] [Haut de page]

© CHU de Rouen. Toute utilisation partielle ou totale de ce document doit mentionner la source.