Melanoma Antigen Recognized by T-Cells 1

Preferred Label : Melanoma Antigen Recognized by T-Cells 1;

NCIt synonyms : MLANA; MART1; Antigen SK29-AA; Antigen LB39-AA; Melan-A; MART-1;

NCIt related terms : Melanoma Antigen Recognized by T cells 1; Melan-A protein;

NCIt definition : Melanoma antigen recognized by T-cells 1 (118 aa, 13 kDa) is encoded by the human MLANA gene. This protein may play a role in melanin production.;

Alternative definition : NCI-GLOSS: A protein found on normal melanocytes (cells that make the pigment melanin) in the skin and in the retina. It is also found on most melanomas (cancers that begin in melanocytes). Vaccines using pieces of the Melan-A protein are being studied for their ability to boost the immune response to cancer cells in patients with melanoma.;

Codes from synonyms : CDR0000626385; CDR0000523285;

Details

Origin ID

C33992;

UMLS CUI

C1744226;

OMIM relation
- Melan a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- MART-1 [LOINC component]
- MART-1 antigen [MeSH concept]
- MART-1 antigen [MeSH Descriptor]
- MLANA protein, human [MeSH Supplementary Concept]
- MLANA protein, human [MeSH concept]
- Melan-A [LOINC component]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Immunoprotein Gene [NCIt concept]
- MLANA Gene [NCIt concept]
gene_product_plays_role_in_biological_process
- Immune System Process [NCIt concept]
- Melanogenesis [NCIt concept]
is_target
- 27-35(27L):MART-1 Peptide [NCIt concept]
- 6 Melanoma Helper Peptide Vaccine [NCIt concept]
- Adenovirus Encoding Tyrosinase/MART-1/MAGEA6-transduced Autologous Dendritic Cell Vaccine [NCIt concept]
- Anti-MART-1 TCR Retroviral Vector-Transduced Autologous TIL [NCIt concept]
- Autologous Anti-MART-1 F5 T-Cell Receptor Gene-Engineered Peripheral Blood Lymphocytes [NCIt concept]
- Autologous Anti-MART-1 F5 TCR Tumor Infiltrating Lymphocytes [NCIt concept]
- Autologous Dendritic Cell-Allogeneic Melanoma Tumor Cell Lysate Vaccine [NCIt concept]
- Dendritic Cell-MART-1 Peptide Vaccine [NCIt concept]
- Immunotherapy Regimen MKC-1106-MT [NCIt concept]
- KLH/NY-ESO-1/MART-1 Peptide-pulsed Dendritic Cell Vaccine [NCIt concept]
- MART-1 Antigen [NCIt concept]
- MART-1 Reactive CD8+ T-lymphocytes [NCIt concept]
- MART-1:26-35(27L) Peptide Vaccine [NCIt concept]
- MART-1:27-35 Peptide Vaccine [NCIt concept]
- Montanide ISA-51 VG/KLH/NY-ESO-1/MART-1 Peptide Vaccine [NCIt concept]

Keyword's position in hierarchy(ies) :

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