27-35(27L):MART-1 Peptide

Preferred Label : 27-35(27L):MART-1 Peptide;

NCIt synonyms : 27-35(27L):MART-1; 27-35 27L MART-1;

NCIt definition : A synthetic peptide consisting of amino acids 27 through 35 of the melanoma differentiation antigen MART-1. 27-35(27L) MART-1 has a leucine substitution at amino acid position 27 to improve binding to HLA-A*0201. Vaccination with this agent may stimulate the host immune response to mount a cytotoxic T-lymphocyte response against melanoma cells expressing MART-1.;

NSC code : 726585;

Details

Origin ID

C28784;

UMLS CUI

C1710929;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_abnormal_cell
- Melanoma Cell [NCIt concept]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
has_target
- Melanoma Antigen Recognized by T-Cells 1 [NCIt concept]

Keyword's position in hierarchy(ies) :

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