Rap Guanine Nucleotide Exchange Factor 1

Preferred Label : Rap Guanine Nucleotide Exchange Factor 1;

NCIt synonyms : C3G Protein; Guanine Nucleotide-Releasing Factor 2; GRF2; CRK SH3-binding GNRP; Rap Guanine Nucleotide Exchange Factor (GEF) 1; Guanine Nucleotide-Releasing Factor-2; Protein C3G; RAPGEF1;

NCIt definition : Rap guanine nucleotide exchange factor 1 (1077 aa, 121 kDa) is encoded by the human RAPGEF1 gene. This protein is involved in guanine nucleotide exchange activity.;

Details

Origin ID

C26236;

UMLS CUI

C1522502;

Currated CISMeF NLP mapping
- guanine Nucleotide-Releasing factor 2 [MeSH Descriptor]
- guanine Nucleotide-Releasing factor 2 [MeSH concept]
OMIM relation
- Rap guanine nucleotide exchange factor 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- RAPGEF1 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- RAPGEF1 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- SH3-Binding Motif [NCIt concept]
gene_product_is_element_in_pathway
- Focal Adhesion Pathway [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway BioCarta [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Integrin Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Renal Cell Carcinoma Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Post-Translational Modification [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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